Medical near-infrared imaging
نویسنده
چکیده
The use of near-infrared light in functional medical imaging has gained increasing interest during recent years. Techniques using near-infrared light for imaging can be used to study, e.g., hemodynamic responses on the cortex. Brain activation measurements can be performed using, e.g., MEG or fMRI, which, however, require heavy instrumentation. In medical near-infrared imaging, the instrumentation can be made quite small in size and the costs can also be kept relatively low, which makes portable devices and the use of the technique for long-time monitoring possible. Due to no significant interference with biomagnetic measurements, the method can be combined with other modalities. Therefore, near-infrared imaging is an interesting alternative in performing or verifying brain activation measurements. In the following, we first describe the principal idea of medical near-infrared imaging and spectroscopy. We then outline the different measurement techniques and some aspects concerning the propagation of nearinfrared light in tissue, especially considering the use of the method for imaging. The developments in modeling and instrumentation in our laboratory are then presented. A light transport model is described, and an approach to image reconstruction based on linearization is outlined. The basic design of the frequency domain imager and observation about its performance are presented.
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